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Your items may arrive sooner than the estimated delivery date. Ralph Lauren reserves the right to send packages via other shipping methods based on the shipping destination as long as orders will still arrive within the arrival times outlined on RalphLauren.com.
When you choose the Economy delivery option, packages are delivered Monday through Saturday 8 AM to 4:30 PM. Orders sent by Fast, 2-Business-Day or Next-Day shipping methods are delivered Monday through Friday from 8 AM to 4:30 PM.
We recommend choosing Fast or Next-Day delivery if you are shipping your package to a business address. You will be asked to provide a telephone number on the shipping page of checkout, which is important in the event the courier needs to arrange a delivery time with you.
You will also be asked to provide an email address, to which we will send confirmation that your order was placed.
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It is not fully understood how paracetamol produces these effects. Codeine belongs to group of medicines called opioids. Opioids mimic the effects of naturally occurring pain reducing chemicals (endorphins) that are found in the brain and spinal cord. They act on the opioid receptors in the brain and block the transmission of pain signals. Therefore, even though the cause of the pain may remain, less pain is actually felt.
Caffeine is a weak stimulant. It is thought that the addition of caffeine may enhance the analgesic effects of paracetamol and codeine.
Doxylamine is a sedating anti-histamine. It acts by blocking the action of histamine which is a chemical released when an allergic response occurs.
Histamine is the chemical in the body that causes the symptoms of an allergic reaction. These can include inflammation of the skin, airways or tissues, rashes, itching of the skin, eyes or nose, nasal congestion and narrowing of the airways. By blocking the actions of histamine, doxylamine prevents and relieves the typical symptoms of an allergic reaction. Sedation is a common effect of doxylamine. As a result it is commonly used in pain relief preparations to encourage sleep. This medicine is used for the treatment of mild to moderate pain and to reduce a high temperature.
Each tablet contains:
Paracetamol | 450 mg | |
Codeine Phosphate | 10 mg | |
Caffeine | 45 mg | |
Doxylamine Succinate | 5 mg |
Also contains E110 (sunset yellow), E104 (quinoline yellow) and lactose monohydrate
For the short term treatment of acute moderate pain where other pain killers have not worked. Do not take less than four hours after taking other pain killers. For tension headaches, migraines, muscular pains and tension.
As with any product that contain doxylamine succinate and/or codeine, do not drive or operate heavy machinery after taking it, consume clear fluids to help prevent constipation and dehydration, and remember that codeine is a narcotic and is habit forming and should not be taken for prolong periods of time.