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Indications
The prevention and treatment of candidal infections of the oral cavity, oesophagus and intestinal tract.
The suspension also provides effective prophylaxis against oral candidosis in those born of mothers with vaginal candidosis.
Nystatin topical preparations are indicated in the treatment of cutaneous or mucocutaneous mycotic infections caused by Candida albicans and other susceptible Candida species.
These preparations are not indicated for systemic, oral, intravaginal or ophthalmic use.
Posology
Oral Candidiasis
Infants (1 month to 2 years)
1ml should be dropped into the mouth four times a day.
Children (> 2 years) and adults
For the treatment of denture sores, and oral infections in children (> 2 years) and adults caused by candidas albicans. 1ml of the suspension should be dropped into the mouth four times daily; it should be kept in contact with the affected areas as long as possible.
Intestinal candidiasis
Infants (1 month to 2 years)
1ml should be dropped into the mouth four times a day.
Adults
For the treatment of intestinal candidosis 5ml of the suspension should be dropped into the mouth four times daily.
Paediatric population (> 2 years)
1ml should be dropped into the mouth four times a day.
For prophylaxis a total daily dosage of 1 million units has been found to suppress the overgrowth of candidas albicans in patients receiving broad-spectrum antibiotic therapy.
For prophylaxis in the newborn the suggested dose is 1ml once daily.
The longer the suspension is kept in contact with the affected area in the mouth before swallowing, the greater will be its effect.
Administration should be continued for 48 hours after clinical cure to prevent relapse.
Older people
No specific dosage recommendations or precautions.
If signs and symptoms worsen or persist (beyond 14 days of treatment), the patient should be reevaluated, and alternate therapy considered.
Very moist lesions are best treated with the topical dusting powder.
Adults and Pediatric Patients (Neonates and Older): Apply liberally to affected areas twice daily or as indicated until healing is complete.
Adults and Pediatric Patients (Neonates and Older): Apply to candidal lesions two or three times daily until healing is complete. For fungal infection of the feet caused by Candida species, the powder should be dusted on the feet, as well as, in all foot wear.