Microval 28 Tablets

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MICROVAL® TabletsSCHEDULING STATUS:S2PROPRIETARY NAME(and dosage form):MICROVAL® TabletsCOMPOSITION:Each sugar-coated tablet contains 30 µg levonorgestrel.PHARMACOLOGICAL CLASSIFICATION:Category A, 18.8 Ovulation controlling agents.PHARMACOLOGICAL ACTION:MICROVAL (levonorgestrel) is thought to have a threefold contraceptive action: Impaired sperm migration; interference with implantation and reduction of corpus luteum function.MICROVAL’s (levonorgestrel) action, believed to be more local than central, without consistently...
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(and dosage form):


Each sugar-coated tablet contains 30 µg 

Category A, 18.8 Ovulation controlling agents.

MICROVAL (levonorgestrel) is thought to have a threefold contraceptive action: Impaired sperm migration; interference with implantation and reduction of corpus luteum function.
MICROVAL’s (levonorgestrel) action, believed to be more local than central, without consistently inhibiting ovulation, may interfere to a lesser extent with the hypothalamic-ovarian axis.

MICROVAL (levonorgestrel) tablets are indicated for the control of fertility.

Oral contraceptives are contra-indicated in patients with recurrent cholestatic jaundice, or markedly impaired liver function, hormone-dependent neoplasms, previous thromboembolic disorders, severe migraine or cerebrovascular insufficiency and undiagnosed vaginal bleeding. Medication should be discontinued immediately if migraine becomes focal, or there is a loss of vision, or if there is an onset of unexplained chest pain. Relative contra-indications include a history of diabetes mellitus, epilepsy, asthma, hypertension, depression, porphyria or states in which fluid retention occur.
Combined oral contraceptives should be avoided in pregnancy and in patients who are breast feeding.

See Side-effects and Special Precautions.

MICROVAL (levonorgestrel) must be taken exactly as directed and at intervals not exceeding 24 hours. Patients should be instructed to take the tablets at the same time every day, preferably after the evening meal or at bedtime.
The patient begins MICROVAL (levonorgestrel) on day 1 of her menstrual cycle, i.e. the first day of bleeding. One tablet is taken every day at the same time, without interruption, as long as contraception is desired. Tablets should be taken on this continuous daily regimen whether or not bleeding occurs. A mechanical method of contraception should be used until the first fourteen tablets have been taken.
Missed tablets:
The risk of pregnancy increases with each tablet missed. If the patient misses one tablet she should be instructed to take it as soon as she remembers and to also take her next tablet at the regular time. If she misses two tablets, she should take one of the missed tablets as soon as she remembers as well as taking her regular tablet for that day at the proper time. In either case, she should use a mechanical method of contraception until fourteen consecutive tablets have been taken. If she has missed one or two tablets and does not have a period within 45 days of her last, she should discontinue MICROVAL (levonorgestrel) and depend upon a mechanical method of contraception until the possibility of pregnancy has been excluded. If more than two tablets have been missed, MICROVAL (levonorgestrel) should be discontinued immediately and a mechanical method of contraception should be used until menses has appeared or the possibility of pregnancy has been excluded. Alternatively, if the patient has taken the tablets correctly and if menses does not appear within 60 days from the last period, a mechanical method of contraception should be substituted until an appropriate diagnostic procedure is performed to exclude the possibility of pregnancy.


1. The incidence of diseases of the circulatory system in women using combined oral contraceptives is significantly greater than that of controls, and the mortality is slightly increased. Coronary thrombosis, cerebrovascular incident and venous thrombosis are more likely to occur in women aged 35 years or over, particularly if they have used the contraceptive for longer than five years, if they smoke, it they are obese or if they are hypertensive. Additional risk factors are diabetes mellitus, hypercholesterolaemia and familia hyperlipoproteinaemia. However, the risk of mortality due to oral contraceptives in women under 35 who are in the high-risk group is in general far less than the risk of mortality due to pregnancy.
2. Hypertension may occur in association with the use of oral contraceptives. Regular blood pressure checks, including a pre-treatment level, are advisable.
3. Prolonged amenorrhoea following the use of oral contraceptives may occur. The incidence is in the order of 1 % of users. Caution is advised where oligomenorrhoea or amenorrhoea have occurred in the past.
4. Mood changes, mass gain, skin pigmentation, vaginal candidiasis, gall bladder disease, gastro-intestinal irritation and fluid retention may occur.
5. Case reports have been published of benign hepatic tumours in women on oral contraceptives for a prolonged time, but a causal relationship has not been established. The preparation should be discontinued if persistent upper abdominal pain develops.
6. Interactions with other drugs and efficacy:
  The efficacy of the contraceptive pill may be decreased when it is administered concomitantly with other drugs such as anti-epileptic agents, rifampicin, phenylbutazone and ampicillin. With vomiting or diarrhoea, the absorption of oral contraceptives may be diminished and women should be advised to use additional methods of contraception at the time of such disorders.
7. Effects on laboratory tests:
  Oral contraceptives may interfere with some laboratory estimations, in particular hormones, glucose tolerance, thyroid function, blood coagulation, serum triglycerides and liver function tests.
8. Surgery is more likely to be associated with an increased incidence of thrombotic side-effects. Adequate precaution should be taken.


NOTE: Under no circumstances should the oral contraceptive tablet be stopped without having adopted a satisfactory alternative method of contraception.

Symptomatic treatment is recommended.

Each pack of MICROVAL (levonorgestrel) contains 28 white, bi-convex, coated tablets.

MICROVAL (levonorgestrel) is obtainable in packs of 28 tablets.

Store in a cool (below 25°C). dry place. Keep out of reach of children.

No more returns on international orders

Please note that due to new Covid-19 related rules, the South African Government no longer allows returns of medicines from abroad. If your parcel is refused entry into your country and marked "Return-to-Shipper", we will not be able to receive your returned parcel. Instead it will be destroyed by the S.A Customs Department upon arrival.

How to return an item from within South Africa

If you need to return an item, please follow these simple steps

28 day cooling off period

If you would like to return an item please notify us within 14 days of your order being delivered. You then have a further 14 days to return the item back to us. This gives you a maximum of 28 days in total to return an item.

You can contact us by completing the form on our contact us page, selecting 'returns' from the drop-down menu. Alternatively, you can notify a member of our Customer Care team on 011 568 3064.

Please note that we are unable to accept returns for the following unless they are damaged or faulty:

  • Perishable items.
  • Unsealed items with a protective seal due to health protection or hygiene reasons.
  • Medicinal products or services that are dispensed on prescription.

Please note, this does not affect your statutory rights.

Where do I send returns?

Once our Customer Care team have been notified, please arrange postage to:

F.A.O: Returns Department
25 Adderley St
Cape Town City Centre
Cape Town
South Africa.

Unfortunately, we're unable to cover the costs of returning your items and cannot be liable for any damages incurred during transit. Please ensure they are properly secured and packaged and we'd recommend sending all returns via a recorded delivery service.

How long will it take to process my refund?

We aim to process your refund within 3-5 working days of receiving your item, however it can take up to 30 days to receive the refund via the original payment method.

Once you've cancelled the contract, you have a legal 'duty of care' to keep the items in a good condition and return them at your expense. We are entitled to deduct an amount from the refund to reflect any loss of revenue in the value of goods supplied which may be 100%, if the loss is the result of unnecessary handling of the goods by you.

In accordance with the Consumer Protection Act, Regulations 68 of 2008, we will refund you the full amount paid for the items returned within 14 days of receipt of the notice of cancellation.

To read out full terms and conditions, please click here.

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Microval 28 Tablets
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