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Your items may arrive sooner than the estimated delivery date. Ralph Lauren reserves the right to send packages via other shipping methods based on the shipping destination as long as orders will still arrive within the arrival times outlined on RalphLauren.com.
When you choose the Economy delivery option, packages are delivered Monday through Saturday 8 AM to 4:30 PM. Orders sent by Fast, 2-Business-Day or Next-Day shipping methods are delivered Monday through Friday from 8 AM to 4:30 PM.
We recommend choosing Fast or Next-Day delivery if you are shipping your package to a business address. You will be asked to provide a telephone number on the shipping page of checkout, which is important in the event the courier needs to arrange a delivery time with you.
You will also be asked to provide an email address, to which we will send confirmation that your order was placed.
Depuran Senna 20 Capsules is a laxative that offers gentle yet effective relief of constipation and the discomfort associated with it.
Depuran has been used in alternative medicine as an aid to treat constipation.
Depuran is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Laxative especially in cases requiring the maintenance
of a soft stool to avoid straining (e.g. When there has
been hernia, aneurysm, hypertension, myocardial
infarction, or cerebrovascular accident, or after a
haemorrhoidectomy or abdominal surgery).
It is also used as an emollient and moisturizer to prevent
or relieve the signs and symptoms of dry skin.
Use Depuran as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Depuran by mouth with or without food.
Ask your health care provider any questions you may have about how to use Depuran.
Syrup:
8.8 mg/5 mL:
10 to 15 mL (17.6 to 26.4 mg) orally once a day, not to exceed 15 mL (26.4 mg) twice a day
176 mg/5 mL:
10 to 15 mL (352 to 528 mg) orally once a day, not to exceed 15 mL (528 mg) twice a day
Tablets:
8.6 mg:
2 tablets (17.2 mg) orally at bedtime, not to exceed 4 tablets (34.4 mg) twice a day
17.2 mg:
1 tablet (17.2 mg) orally at bedtime, not to exceed 2 tablets (34.4 mg) twice a day
25 mg:
2 tablets (50 mg) orally once or twice a day
17 mg:
1 tablet (17 mg) orally, not to exceed 2 tablets (34 mg) twice a day
15 mg:
2 tablets (30 mg) orally once or twice a day
Oral:
Syrup:
8.8 mg/5 mL:
10 to 15 mL (17.6 to 26.4 mg) orally once a day, not to exceed 15 mL (26.4 mg) twice a day
176 mg/5 mL:
10 to 15 mL (352 to 528 mg) orally once a day, not to exceed 15 mL (528 mg) twice a day
Tablets:
8.6 mg:
2 tablets (17.2 mg) orally at bedtime, not to exceed 4 tablets (34.4 mg) twice a day
17.2 mg:
1 tablet (17.2 mg) orally at bedtime, not to exceed 2 tablets (34.4 mg) twice a day
25 mg:
2 tablets (50 mg) orally once or twice a day
17 mg:
1 tablet (17 mg) orally, not to exceed 2 tablets (34 mg) twice a day
15 mg:
2 tablets (30 mg) orally once or twice a day
10 to 20 mg/kg/dose orally at bedtime, not to exceed 872 mg
Tablets:
8.6 mg:
2 to less than 6 years: 1/2 tablet (4.3 mg) orally at bedtime, not to exceed 1 tablet (8.6 mg) twice a day
6 to less than 12 years: 1 tablet (8.6 mg) orally at bedtime, not to exceed 2 tablets (17.2 mg) twice a day
12 to less than 18 years: 2 tablets (17.2 mg) orally at bedtime, not to exceed 4 tablets (34.4 mg) twice a day
17.2 mg:
6 to less than 12 years: 1/2 tablet (8.6 mg) orally at bedtime, not to exceed 1 tablet (17.2 mg) twice a day
12 to less than 18 years: 1 tablet (17.2 mg) orally at bedtime, not to exceed 2 tablets (34.4 mg) twice a day
25 mg:
6 to less than 12 years: 1 tablet (25 mg) orally once or twice a day
12 to less than 18 years: 2 tablets (50 mg) orally once or twice a day
17 mg:
6 to less than 12 years: 1/2 tablet (8.5 mg) orally, not to exceed 1 tablet (17 mg) twice a day
12 to less than 18 years: 1 tablet (17 mg) orally, not to exceed 2 tablets (34 mg) twice a day
15 mg:
6 to less than 12 years: 1 tablet (15 mg) orally once or twice a day
12 to less than 18 years: 2 tablets (30 mg) orally once or twice a day
Syrup:
8.8 mg/5 mL:
2 to less than 6 years: 2.5 to 3.75 mL (4.4 to 6.6 mg) orally once a day, not to exceed 3.75 mL (6.6 mg) twice a day
6 to less than 12 years: 5 to 7.5 mL (8.8 to 13.2 mg) orally once a day, not to exceed 7.5 mL (13.2 mg) twice a day
12 to less than 18 years: 10 to 15 mL (17.6 to 26.4 mg) orally once a day, not to exceed 15 mL (26.4 mg) twice a day
176 mg/5 mL:
2 to less than 6 years: 2.5 to 3.75 mL (87.5 to 132 mg) orally once a day, not to exceed 3.75 mL (132 mg) twice a day
6 to less than 12 years: 5 to 7.5 mL (176 to 263.5 mg) orally once a day, not to exceed 7.5 mL (263.5 mg) twice a day
12 to less than 18 years: 10 to 15 mL (352 to 528 mg) orally once a day, not to exceed 15 mL (528 mg) twice a day
Liquid:
33.3 mg/mL:
2 to 6 years: 5 to 10 mL (166.5 to 333 mg) orally 1 to 2 times a day
6 to 15 years: 10 to 15 mL (333 to 499.5 mg) orally 1 to 2 times a day
Strips:
8.6 mg:
2 to 6 years: 1 strip (8.6 mg) orally per day, not to exceed 2 strips (17 mg) per day
6 to 12 years: 2 strips (17 mg) orally per day, not to exceed 4 (68 mg) strips per day
Oral:
10 to 20 mg/kg/dose orally at bedtime, not to exceed 872 mg
Tablets:
8.6 mg:
2 to less than 6 years: 1/2 tablet (4.3 mg) orally at bedtime, not to exceed 1 tablet (8.6 mg) twice a day
6 to less than 12 years: 1 tablet (8.6 mg) orally at bedtime, not to exceed 2 tablets (17.2 mg) twice a day
12 to less than 18 years: 2 tablets (17.2 mg) orally at bedtime, not to exceed 4 tablets (34.4 mg) twice a day
17.2 mg:
6 to less than 12 years: 1/2 tablet (8.6 mg) orally at bedtime, not to exceed 1 tablet (17.2 mg) twice a day
12 to less than 18 years: 1 tablet (17.2 mg) orally at bedtime, not to exceed 2 tablets (34.4 mg) twice a day
25 mg:
6 to less than 12 years: 1 tablet (25 mg) orally once or twice a day
12 to less than 18 years: 2 tablets (50 mg) orally once or twice a day
17 mg:
6 to less than 12 years: 1/2 tablet (8.5 mg) orally, not to exceed 1 tablet (17 mg) twice a day
12 to less than 18 years: 1 tablet (17 mg) orally, not to exceed 2 tablets (34 mg) twice a day
15 mg:
6 to less than 12 years: 1 tablet (15 mg) orally once or twice a day
12 to less than 18 years: 2 tablets (30 mg) orally once or twice a day
Syrup:
8.8 mg/5 mL:
2 to less than 6 years: 2.5 to 3.75 mL (4.4 to 6.6 mg) orally once a day, not to exceed 3.75 mL (6.6 mg) twice a day
6 to less than 12 years: 5 to 7.5 mL (8.8 to 13.2 mg) orally once a day, not to exceed 7.5 mL (13.2 mg) twice a day
12 to less than 18 years: 10 to 15 mL (17.6 to 26.4 mg) orally once a day, not to exceed 15 mL (26.4 mg) twice a day
176 mg/5 mL:
2 to less than 6 years: 2.5 to 3.75 mL (87.5 to 132 mg) orally once a day, not to exceed 3.75 mL (132 mg) twice a day
6 to less than 12 years: 5 to 7.5 mL (176 to 263.5 mg) orally once a day, not to exceed 7.5 mL (263.5 mg) twice a day
12 to less than 18 years: 10 to 15 mL (352 to 528 mg) orally once a day, not to exceed 15 mL (528 mg) twice a day
Liquid:
33.3 mg/mL:
2 to 6 years: 5 to 10 mL (166.5 to 333 mg) orally 1 to 2 times a day
6 to 15 years: 10 to 15 mL (333 to 499.5 mg) orally 1 to 2 times a day
Strips:
8.6 mg:
2 to 6 years: 1 strip (8.6 mg) orally per day, not to exceed 2 strips (17 mg) per day
6 to 12 years: 2 strips (17 mg) orally per day, not to exceed 4 (68 mg) strips per day
Depuran is not recommended when abdominal pain, nausea, or vomiting, or a sudden change in bowel habits are present. Long-term administration of Depuran is not recommended for the treatment of chronic constipation. Rectal bleeding or failure to have a bowel movement after Depuran use may indicate a serious underlying gastrointestinal condition, and warrants discontinuation of therapy and evaluation.
Case reports of severe diaper rash, blisters, and skin sloughing have been reported in pediatric patients who were administered suppositories. These effects have been more prevalent in children wearing diapers. Prompt changing of diapers, frequent cleansing of perianal area, and application of barrier ointment may help reduce the incidence and severity.